Galectin-3 expression in macrophages is signaled by Ras/MAP kinase pathway and up-regulated by modified lipoproteins.

Kim, Koanhoi; Mayer, Eugene P; Nachtigal, Maurice

Kim, Koanhoi; Mayer, Eugene P; Nachtigal, Maurice.

Affiliation

Kim K; Department of Pathology and Microbiology, University of South Carolina-School of Medicine, Columbia, SC 29208, USA.

Biochim Biophys Acta ; 1641(1): 13-23, 2003 Jun 17.

Article in En | MEDLINE | ID: mdl-12788225

Subject(s)

Galectin 3/metabolism; Gene Expression Regulation/drug effects; MAP Kinase Signaling System/physiology; Macrophages, Peritoneal/metabolism; Signal Transduction; ras Proteins/metabolism; Animals; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors/pharmacology; Genes, jun/drug effects; MAP Kinase Kinase 1; Macrophages, Peritoneal/cytology; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors; Protein Kinase C/antagonists & inhibitors; Protein Serine-Threonine Kinases/antagonists & inhibitors; Proto-Oncogene Proteins c-jun/metabolism; Rabbits; Tetradecanoylphorbol Acetate/pharmacology; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Gene Expression Regulation / Macrophages, Peritoneal / Ras Proteins / MAP Kinase Signaling System / Galectin 3 Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 2003 Document type: Article Affiliation country: United States Country of publication: Netherlands

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