Immunoglobulins inhibit pathophysiological effects of anti-GQ1b-positive sera at motor nerve terminals through inhibition of antibody binding.

Jacobs, Bart C; O'Hanlon, Graham M; Bullens, Roland W M; Veitch, Jean; Plomp, Jaap J; Willison, Hugh J

Jacobs, Bart C; O'Hanlon, Graham M; Bullens, Roland W M; Veitch, Jean; Plomp, Jaap J; Willison, Hugh J.

Affiliation

Jacobs BC; Department of Neurology, Erasmus Medical Centre, Rotterdam, The Netherlands. b.jacobs@erasmusmc.nl

Brain ; 126(Pt 10): 2220-34, 2003 Oct.

Article in En | MEDLINE | ID: mdl-12876146

Subject(s)

Antibodies/metabolism; Gangliosides/immunology; Immunoglobulins, Intravenous; Motor Neurons/immunology; Neuromuscular Diseases/drug therapy; Neuromuscular Junction/immunology; Antibodies/analysis; Biological Assay; Complement Activation; Complement C1q/analysis; Enzyme-Linked Immunosorbent Assay/methods; Guillain-Barre Syndrome/drug therapy; Guillain-Barre Syndrome/immunology; Humans; Immunoglobulin G/immunology; Miller Fisher Syndrome/drug therapy; Miller Fisher Syndrome/immunology; Muscle Contraction; Neuromuscular Diseases/immunology; Statistics, Nonparametric

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulins, Intravenous / Gangliosides / Antibodies / Motor Neurons / Neuromuscular Diseases / Neuromuscular Junction Type of study: Prognostic_studies Limits: Humans Language: En Journal: Brain Year: 2003 Document type: Article Affiliation country: Netherlands

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