Transient down-modulation of CD20 by rituximab in patients with chronic lymphocytic leukemia.

Jilani, Iman; O'Brien, Susan; Manshuri, Taghi; Thomas, Deborah A; Thomazy, Vilmos A; Imam, Maha; Naeem, Sana; Verstovsek, Srdan; Kantarjian, Hagop; Giles, Francis; Keating, Michael; Albitar, Maher

Jilani, Iman; O'Brien, Susan; Manshuri, Taghi; Thomas, Deborah A; Thomazy, Vilmos A; Imam, Maha; Naeem, Sana; Verstovsek, Srdan; Kantarjian, Hagop; Giles, Francis; Keating, Michael; Albitar, Maher.

Affiliation

Jilani I; Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, USA.

Blood ; 102(10): 3514-20, 2003 Nov 15.

Article in En | MEDLINE | ID: mdl-12893761

Subject(s)

Antibodies, Monoclonal/pharmacology; Antigens, CD20/biosynthesis; Down-Regulation/drug effects; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy; Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/therapeutic use; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20/genetics; B-Lymphocytes/chemistry; Cytoplasm/chemistry; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell/pathology; RNA, Messenger/analysis; Rituximab; Time Factors; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Down-Regulation / Antigens, CD20 / Antibodies, Monoclonal Limits: Humans Language: En Journal: Blood Year: 2003 Document type: Article Affiliation country: United States Country of publication: United States

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