Divergent envelope E2 alphavirus sequences spanning amino acids 297 to 352 induce in mice virus-specific protective immunity and antibodies with complement-mediated cytolytic activity.

Grosfeld, H; Lustig, S; Gozes, Y; Velan, B; Cohen, S; Leitner, M; Lachmi, B; Katz, D; Olshevski, U; Shafferman, A

Grosfeld, H; Lustig, S; Gozes, Y; Velan, B; Cohen, S; Leitner, M; Lachmi, B; Katz, D; Olshevski, U; Shafferman, A.

Affiliation

Grosfeld H; Department of Biochemistry, Israel Institute for Biological Research, Ness-Ziona.

J Virol ; 66(2): 1084-90, 1992 Feb.

Article in En | MEDLINE | ID: mdl-1309890

Subject(s)

Alphavirus/immunology; Antibody-Dependent Cell Cytotoxicity; Complement System Proteins/immunology; Cytotoxicity, Immunologic; Semliki forest virus/immunology; Viral Envelope Proteins/immunology; Viral Vaccines/immunology; Algorithms; Alphavirus/pathogenicity; Amino Acid Sequence; Animals; Cell Line; Enzyme-Linked Immunosorbent Assay; Female; Immunization; Mice; Mice, Inbred ICR; Molecular Sequence Data; Protein Conformation; Semliki forest virus/pathogenicity; Sequence Homology, Nucleic Acid; Species Specificity; Vero Cells; Viral Envelope Proteins/genetics; Viral Plaque Assay; Virulence/immunology; beta-Galactosidase/genetics; beta-Galactosidase/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Semliki forest virus / Complement System Proteins / Viral Vaccines / Viral Envelope Proteins / Alphavirus / Cytotoxicity, Immunologic / Antibody-Dependent Cell Cytotoxicity Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Virol Year: 1992 Document type: Article

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