Increased levels of tissue plasminogen activator (t-PA) and tissue plasminogen activator inhibitor (PAI) correlate with tumor necrosis factor alpha (TNF alpha)-release in patients suffering from microangiopathy following allogeneic bone marrow transplantation (BMT).

Seeber, C; Hiller, E; Holler, E; Kolb, H J

Seeber, C; Hiller, E; Holler, E; Kolb, H J.

Affiliation

Seeber C; Medizinische Klinik III, Ludwig-Maximilians-Universität München, FRG.

Thromb Res ; 66(4): 373-83, 1992 May 15.

Article in En | MEDLINE | ID: mdl-1412203

Subject(s)

Bone Marrow Transplantation/adverse effects; Cyclosporine/adverse effects; Graft vs Host Disease/blood; Plasminogen Activator Inhibitor 1/analysis; Tissue Plasminogen Activator/analysis; Tumor Necrosis Factor-alpha/metabolism; Vascular Diseases/blood; Acute Disease; Adult; Cyclosporine/therapeutic use; Factor VIII/analysis; Fibrin Fibrinogen Degradation Products/analysis; Graft vs Host Disease/drug therapy; Humans; Microcirculation; Middle Aged; Platelet Factor 4/analysis; Prospective Studies; Severity of Illness Index; Transplantation, Autologous; Transplantation, Homologous; beta-Thromboglobulin/analysis; von Willebrand Factor/analysis

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Collection: 01-internacional Database: MEDLINE Main subject: Vascular Diseases / Bone Marrow Transplantation / Tumor Necrosis Factor-alpha / Cyclosporine / Tissue Plasminogen Activator / Plasminogen Activator Inhibitor 1 / Graft vs Host Disease Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Humans / Middle aged Language: En Journal: Thromb Res Year: 1992 Document type: Article

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