Simultaneous determination of omeprazole and its metabolites in plasma and urine by reversed-phase high-performance liquid chromatography with an alkaline-resistant polymer-coated C18 column.

Kobayashi, K; Chiba, K; Sohn, D R; Kato, Y; Ishizaki, T

Kobayashi, K; Chiba, K; Sohn, D R; Kato, Y; Ishizaki, T.

Affiliation

Kobayashi K; Division of Clinical Pharmacology, National Medical Center, Tokyo, Japan.

J Chromatogr ; 579(2): 299-305, 1992 Sep 02.

Article in En | MEDLINE | ID: mdl-1429977

Subject(s)

Chromatography, High Pressure Liquid/methods; Omeprazole/blood; Omeprazole/urine; Adult; Carbon; Drug Resistance; Humans; Hydroxides; Liver/metabolism; Male; Omeprazole/metabolism; Polymers

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Collection: 01-internacional Database: MEDLINE Main subject: Omeprazole / Chromatography, High Pressure Liquid Limits: Adult / Humans / Male Language: En Journal: J Chromatogr Year: 1992 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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