MPP+ analogs acting on mitochondria and inducing neuro-degeneration.

Kotake, Y; Ohta, S

Kotake, Y; Ohta, S.

Affiliation

Kotake Y; Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. yaichiro@hiroshima-u.ac.jp

Curr Med Chem ; 10(23): 2507-16, 2003 Dec.

Article in En | MEDLINE | ID: mdl-14529466

Subject(s)

1-Methyl-4-phenylpyridinium/metabolism; 1-Methyl-4-phenylpyridinium/toxicity; Mitochondria/drug effects; Neurons/drug effects; 1-Methyl-4-phenylpyridinium/chemistry; Animals; Electron Transport/drug effects; Electron Transport/physiology; Humans; Isoquinolines/chemistry; Isoquinolines/pharmacology; Mitochondria/metabolism; Neurodegenerative Diseases/chemically induced; Neurons/metabolism; Parkinson Disease, Secondary/cerebrospinal fluid; Rotenone/metabolism; Rotenone/pharmacology; Ubiquinone/metabolism; Ubiquinone/pharmacology; Uncoupling Agents/chemistry; Uncoupling Agents/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: 1-Methyl-4-phenylpyridinium / Mitochondria / Neurons Limits: Animals / Humans Language: En Journal: Curr Med Chem Journal subject: QUIMICA Year: 2003 Document type: Article Affiliation country: Japan Country of publication: United Arab Emirates

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