Extensive changes in liver gene expression induced by hereditary tyrosinemia type I are not normalized by treatment with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC).

Luijerink, Marjanka C; Jacobs, Saskia M M; van Beurden, Ellen A C M; Koornneef, Leander P; Klomp, Leo W J; Berger, Ruud; van den Berg, Inge E T

Luijerink, Marjanka C; Jacobs, Saskia M M; van Beurden, Ellen A C M; Koornneef, Leander P; Klomp, Leo W J; Berger, Ruud; van den Berg, Inge E T.

Affiliation

Luijerink MC; Department of Metabolic Diseases, Laboratory for Metabolic and Endocrine Diseases, Room KC02.069.1, University Medical Center, Lundlaan 6, 3584 EA Utrecht, The Netherlands.

J Hepatol ; 39(6): 901-9, 2003 Dec.

Article in En | MEDLINE | ID: mdl-14642604

Subject(s)

Cyclohexanones/pharmacology; Enzyme Inhibitors/pharmacology; Liver/physiology; Nitrobenzoates/pharmacology; Tyrosinemias/drug therapy; Tyrosinemias/genetics; Animals; Blotting, Northern; DNA, Complementary; Female; Gene Expression/drug effects; Gene Expression Profiling; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenotype; Reproducibility of Results; Tyrosinemias/physiopathology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Tyrosinemias / Cyclohexanones / Enzyme Inhibitors / Liver / Nitrobenzoates Limits: Animals Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2003 Document type: Article Affiliation country: Netherlands Country of publication: Netherlands

Search on Google

Add to My VHL

XML

PubMed Links