A dengue-2 Envelope fragment inserted within the structure of the P64k meningococcal protein carrier enables a functional immune response against the virus in mice.

Hermida, Lisset; Rodríguez, Rayner; Lazo, Laura; Silva, Ricardo; Zulueta, Aída; Chinea, Glay; López, Carlos; Guzmán, María G; Guillén, Gerardo

Hermida, Lisset; Rodríguez, Rayner; Lazo, Laura; Silva, Ricardo; Zulueta, Aída; Chinea, Glay; López, Carlos; Guzmán, María G; Guillén, Gerardo.

Affiliation

Hermida L; División de Vacunas, Centro de Ingeniería Genética y Biotecnología, Apdo 6162, Habana 10600, Cuba. lisset.hermida@cigb.edu.cu

J Virol Methods ; 115(1): 41-9, 2004 Jan.

Article in En | MEDLINE | ID: mdl-14656459

Subject(s)

Bacterial Outer Membrane Proteins/genetics; Dengue Virus/immunology; Dengue/prevention & control; Viral Envelope Proteins/genetics; Viral Vaccines; Animals; Antibodies, Viral/blood; Bacterial Outer Membrane Proteins/chemistry; Bacterial Outer Membrane Proteins/immunology; Bacterial Outer Membrane Proteins/metabolism; Dengue/virology; Escherichia coli/genetics; Escherichia coli/metabolism; Immunization; Mice; Mice, Inbred BALB C; Recombinant Fusion Proteins; Viral Envelope Proteins/immunology; Viral Envelope Proteins/metabolism; Viral Vaccines/administration & dosage; Viral Vaccines/genetics; Viral Vaccines/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Outer Membrane Proteins / Viral Vaccines / Viral Envelope Proteins / Dengue / Dengue Virus Limits: Animals Language: En Journal: J Virol Methods Year: 2004 Document type: Article Affiliation country: Cuba Country of publication: Netherlands

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