Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

Wang, Wei; Ungermannova, Dana; Jin, Jianpin; Harper, J Wade; Liu, Xuedong

Wang, Wei; Ungermannova, Dana; Jin, Jianpin; Harper, J Wade; Liu, Xuedong.

Affiliation

Wang W; Department of Chemistry and Biochemistry, University of Colorado-Boulder, Boulder, CO 80309, USA.

Oncogene ; 23(5): 1064-75, 2004 Feb 05.

Article in En | MEDLINE | ID: mdl-14676846

Subject(s)

Ligases/metabolism; S-Phase Kinase-Associated Proteins/metabolism; Signal Transduction; Transforming Growth Factor beta/pharmacology; Tumor Suppressor Proteins/metabolism; Anaphase-Promoting Complex-Cyclosome; Animals; CDC2-CDC28 Kinases; Carrier Proteins/drug effects; Cell Cycle Proteins/drug effects; Cell Cycle Proteins/metabolism; Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Epithelial Cells/drug effects; Epithelial Cells/metabolism; G1 Phase; Gene Expression Regulation, Enzymologic; Genes, Tumor Suppressor; Glutathione Transferase/metabolism; Lung; Mink; Models, Biological; Protein Kinases/drug effects; Recombinant Proteins/metabolism; Retroviridae/genetics; S Phase; S-Phase Kinase-Associated Proteins/drug effects; Transcription, Genetic/drug effects; Ubiquitin/metabolism; Ubiquitin-Protein Ligase Complexes/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Transforming Growth Factor beta / Tumor Suppressor Proteins / S-Phase Kinase-Associated Proteins / Ligases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2004 Document type: Article Affiliation country: United States

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