Cyclophosphamide treatment modifies tumor oxygenation and glycolytic rates of RIF-1 tumors: 13C magnetic resonance spectroscopy, Eppendorf electrode, and redox scanning.

Poptani, Harish; Bansal, Navin; Jenkins, Walter T; Blessington, Dana; Mancuso, Anthony; Nelson, David S; Feldman, Michael; Delikatny, Edward J; Chance, Britton; Glickson, Jerry D

Poptani, Harish; Bansal, Navin; Jenkins, Walter T; Blessington, Dana; Mancuso, Anthony; Nelson, David S; Feldman, Michael; Delikatny, Edward J; Chance, Britton; Glickson, Jerry D.

Affiliation

Poptani H; Departments of Radiology, Johnson Research Foundation, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. Poptani@oasis.upenn.edu

Cancer Res ; 63(24): 8813-20, 2003 Dec 15.

Article in En | MEDLINE | ID: mdl-14695197

Subject(s)

Cyclophosphamide/pharmacology; Fibrosarcoma/drug therapy; Fibrosarcoma/metabolism; Oxygen/metabolism; Animals; Carbon Isotopes; Cell Division/drug effects; Chromatography, High Pressure Liquid; Female; Fibrosarcoma/blood supply; Glutamic Acid/metabolism; Glycolysis/drug effects; Ion-Selective Electrodes; Magnetic Resonance Spectroscopy/methods; Mice; Mice, Inbred C3H; Mitochondria/metabolism; Mitosis/drug effects; Neovascularization, Pathologic/blood; Neovascularization, Pathologic/diagnostic imaging; Neovascularization, Pathologic/metabolism; Oxidation-Reduction; Oxygen/blood; Oxygen Consumption/drug effects; Ultrasonography

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Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Cyclophosphamide / Fibrosarcoma Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Cancer Res Year: 2003 Document type: Article Affiliation country: United States

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