Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells.

Shao, Jinyi; Evers, B Mark; Sheng, Hongmiao

Shao, Jinyi; Evers, B Mark; Sheng, Hongmiao.

Affiliation

Shao J; Department of Surgery and Sealy Center for Cancer Cell Biology, University of Texas Medical Branch, Galveston Texas 77555, USA.

J Biol Chem ; 279(14): 14287-93, 2004 Apr 02.

Article in En | MEDLINE | ID: mdl-14742435

Subject(s)

Antineoplastic Agents/pharmacology; Colonic Neoplasms; Dinoprostone/pharmacology; ErbB Receptors/metabolism; MAP Kinase Signaling System/drug effects; Transforming Growth Factor alpha/pharmacology; Cell Division/drug effects; Cell Line, Tumor/cytology; Cell Line, Tumor/drug effects; Cell Line, Tumor/physiology; Cell Movement/drug effects; Cyclic AMP Response Element-Binding Protein/metabolism; Cyclooxygenase 2; Drug Synergism; Humans; Isoenzymes/metabolism; MAP Kinase Signaling System/physiology; Membrane Proteins; Promoter Regions, Genetic/physiology; Prostaglandin-Endoperoxide Synthases/metabolism; Proto-Oncogene Proteins c-raf/metabolism; Response Elements/physiology; Sp1 Transcription Factor/metabolism; ras Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Dinoprostone / Transforming Growth Factor alpha / Colonic Neoplasms / MAP Kinase Signaling System / ErbB Receptors / Antineoplastic Agents Limits: Humans Language: En Journal: J Biol Chem Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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