Sorting competition with membrane-permeable peptides in intact epithelial cells revealed discrimination of transmembrane proteins not only at the trans-Golgi network but also at pre-Golgi stages.

Soza, Andrea; Norambuena, Andrés; Cancino, Jorge; de la Fuente, Erwin; Henklein, Peter; González, Alfonso

Soza, Andrea; Norambuena, Andrés; Cancino, Jorge; de la Fuente, Erwin; Henklein, Peter; González, Alfonso.

Affiliation

Soza A; Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, and Centro de Regulación Celular y Patología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, 6510260 Santiago, Chile.

J Biol Chem ; 279(17): 17376-83, 2004 Apr 23.

Article in En | MEDLINE | ID: mdl-14764609

Subject(s)

Cell Membrane/metabolism; Epithelial Cells/metabolism; Peptides/chemistry; trans-Golgi Network/metabolism; Amino Acid Motifs; Amino Acid Sequence; Animals; Biotinylation; Cell Line; Cytosol/metabolism; DNA, Complementary/metabolism; Dogs; Endoplasmic Reticulum/metabolism; ErbB Receptors/chemistry; Gene Products, tat/metabolism; Glycoside Hydrolases/metabolism; Golgi Apparatus/metabolism; Microscopy, Fluorescence; Molecular Sequence Data; Plasmids/metabolism; Proline/chemistry; Protein Sorting Signals; Protein Structure, Tertiary; Protein Transport; Sequence Homology, Amino Acid; Temperature; Time Factors; Transfection; Tyrosine/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Cell Membrane / Trans-Golgi Network / Epithelial Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2004 Document type: Article Affiliation country: Chile Country of publication: United States

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