The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

Roest, Henk P; Baarends, Willy M; de Wit, Jan; van Klaveren, Jan W; Wassenaar, Evelyne; Hoogerbrugge, Jos W; van Cappellen, Wiggert A; Hoeijmakers, Jan H J; Grootegoed, J Anton

Roest, Henk P; Baarends, Willy M; de Wit, Jan; van Klaveren, Jan W; Wassenaar, Evelyne; Hoogerbrugge, Jos W; van Cappellen, Wiggert A; Hoeijmakers, Jan H J; Grootegoed, J Anton.

Affiliation

Roest HP; MGC-Department of Cell Biology and Genetics, Centre for Biomedical Genetics, Erasmus MC, Rotterdam, The Netherlands.

Mol Cell Biol ; 24(12): 5485-95, 2004 Jun.

Article in En | MEDLINE | ID: mdl-15169909

Subject(s)

DNA Repair; Embryonic and Fetal Development/physiology; Ubiquitin-Conjugating Enzymes/physiology; Alleles; Animals; Base Sequence; DNA, Complementary/genetics; Embryonic and Fetal Development/genetics; Female; Fertility; Gene Targeting; Histones/chemistry; Histones/metabolism; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Oocytes/metabolism; Phenotype; Pregnancy; Ubiquitin-Conjugating Enzymes/deficiency; Ubiquitin-Conjugating Enzymes/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Conjugating Enzymes / DNA Repair / Embryonic and Fetal Development Limits: Animals / Pregnancy Language: En Journal: Mol Cell Biol Year: 2004 Document type: Article Affiliation country: Netherlands Country of publication: United States

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