Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phases.

Li, Wenhui; Kim, Soo-Mi; Lee, Joon; Dunphy, William G

Li, Wenhui; Kim, Soo-Mi; Lee, Joon; Dunphy, William G.

Affiliation

Li W; Division of Biology 216-76, California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125, USA.

J Cell Biol ; 165(6): 801-12, 2004 Jun 21.

Article in En | MEDLINE | ID: mdl-15197177

Subject(s)

Adenosine Triphosphatases/deficiency; Adenosine Triphosphatases/genetics; DNA Damage; DNA Helicases/deficiency; DNA Helicases/genetics; Animals; Bloom Syndrome/genetics; Cell Nucleus/physiology; Cell Nucleus/ultrastructure; Chromatin/physiology; Chromatin/ultrastructure; Female; Humans; Male; Methionine/metabolism; Ovum/cytology; RecQ Helicases; S Phase/genetics; S Phase/physiology; Spermatozoa/cytology; Xenopus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Adenosine Triphosphatases / DNA Helicases Limits: Animals / Female / Humans / Male Language: En Journal: J Cell Biol Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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