Neuregulin induces GABAA receptor beta2 subunit expression in cultured rat cerebellar granule neurons by activating multiple signaling pathways.

Xie, Fang; Raetzman, Lori T; Siegel, Ruth E

Xie, Fang; Raetzman, Lori T; Siegel, Ruth E.

Affiliation

Xie F; Department of Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio 44106-4965, USA.

J Neurochem ; 90(6): 1521-9, 2004 Sep.

Article in En | MEDLINE | ID: mdl-15341535

Subject(s)

Cerebellum/cytology; Gene Expression Regulation/drug effects; Neuregulins/pharmacology; Neurons/drug effects; Receptors, GABA-A/metabolism; Signal Transduction/drug effects; Animals; Animals, Newborn; Blotting, Western/methods; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors/pharmacology; Immunohistochemistry/methods; Mitogen-Activated Protein Kinases/metabolism; Neurons/metabolism; Precipitin Tests/methods; Protein Subunits/genetics; Protein Subunits/metabolism; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; Receptors, GABA-A/genetics; Reverse Transcriptase Polymerase Chain Reaction/methods; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Cerebellum / Gene Expression Regulation / Receptors, GABA-A / Neuregulins / Neurons Limits: Animals Language: En Journal: J Neurochem Year: 2004 Document type: Article Affiliation country: United States Country of publication: United kingdom

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