KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32).

Levine, R L; Wadleigh, M; Sternberg, D W; Wlodarska, I; Galinsky, I; Stone, R M; DeAngelo, D J; Gilliland, D Gary; Cools, J

Levine, R L; Wadleigh, M; Sternberg, D W; Wlodarska, I; Galinsky, I; Stone, R M; DeAngelo, D J; Gilliland, D Gary; Cools, J.

Affiliation

Levine RL; Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Leukemia ; 19(1): 27-30, 2005 Jan.

Article in En | MEDLINE | ID: mdl-15496975

Subject(s)

Antineoplastic Agents/therapeutic use; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 5; Myeloproliferative Disorders/drug therapy; Piperazines/therapeutic use; Pyrimidines/therapeutic use; Receptor, Platelet-Derived Growth Factor beta/genetics; Translocation, Genetic; Adult; Amino Acid Sequence; Base Sequence; Benzamides; Cloning, Molecular; DNA Primers; Humans; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Male; Myeloproliferative Disorders/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyrimidines / Translocation, Genetic / Chromosomes, Human, Pair 5 / Chromosomes, Human, Pair 14 / Receptor, Platelet-Derived Growth Factor beta / Myeloproliferative Disorders / Antineoplastic Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Humans / Male Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2005 Document type: Article Affiliation country: United States Country of publication: United kingdom

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