VP22-mediated intercellular transport correlates with enhanced biological activity of MybEngrailed but not (HSV-I) thymidine kinase fusion proteins in primary vascular cells following non-viral transfection.

Sheridan, Paul J; Lawrie, Allan; Crossman, David C; Holt, Cathy M; Newman, Christopher M

Sheridan, Paul J; Lawrie, Allan; Crossman, David C; Holt, Cathy M; Newman, Christopher M.

Affiliation

Sheridan PJ; Cardiovascular Research Unit, Division of Clinical Sciences (North), Clinical Sciences Centre, University of Sheffield, Northern General Hospital, Sheffield S5 7AU, UK. PaulJohn.Sheridan@btinternet.com

J Gene Med ; 7(3): 375-85, 2005 Mar.

Article in En | MEDLINE | ID: mdl-15543525

Subject(s)

Herpesvirus 1, Human/enzymology; Homeodomain Proteins/metabolism; Muscle, Smooth, Vascular/cytology; Oncogene Proteins v-myb/metabolism; Thymidine Kinase/metabolism; Transcription Factors/metabolism; Transfection; Viral Structural Proteins/metabolism; Animals; Apoptosis; Biological Transport/physiology; Bystander Effect; Cells, Cultured; Gene Transfer Techniques; Genetic Therapy/methods; Homeodomain Proteins/genetics; Muscle, Smooth, Vascular/metabolism; Oncogene Proteins v-myb/genetics; Plasmids/genetics; Plasmids/metabolism; Recombinant Fusion Proteins/metabolism; Swine; Thymidine Kinase/genetics; Transcription Factors/genetics; Transgenes; Viral Structural Proteins/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Thymidine Kinase / Transcription Factors / Transfection / Viral Structural Proteins / Herpesvirus 1, Human / Homeodomain Proteins / Oncogene Proteins v-myb / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: J Gene Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2005 Document type: Article Affiliation country: United kingdom

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