Inhibition of rat liver CYP2D in vitro and after 1-day and long-term exposure to neuroleptics in vivo-possible involvement of different mechanisms.

Daniel, W A; Haduch, A; Wójcikowski, J

Daniel, W A; Haduch, A; Wójcikowski, J.

Affiliation

Daniel WA; Polish Academy of Sciences, Institute of Pharmacology, Smetna 12, 31-343 Kraków, Poland. nfdaniel@cyf-kr.edu.pl

Eur Neuropsychopharmacol ; 15(1): 103-10, 2005 Jan.

Article in En | MEDLINE | ID: mdl-15572279

Subject(s)

Antipsychotic Agents/administration & dosage; Cytochrome P-450 Enzyme System/metabolism; Microsomes, Liver/drug effects; Animals; Cytochrome P-450 Enzyme System/classification; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethylmorphine/metabolism; In Vitro Techniques; Male; Microsomes, Liver/metabolism; Rats; Rats, Wistar; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Antipsychotic Agents / Microsomes, Liver / Cytochrome P-450 Enzyme System Limits: Animals Language: En Journal: Eur Neuropsychopharmacol Journal subject: PSICOFARMACOLOGIA Year: 2005 Document type: Article Affiliation country: Poland Country of publication: Netherlands

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