8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1.

Lomax, Martine E; Salje, Henrik; Cunniffe, Siobhan; O'Neill, Peter

Lomax, Martine E; Salje, Henrik; Cunniffe, Siobhan; O'Neill, Peter.

Affiliation

Lomax ME; Medical Research Council, Radiation and Genome Stability Unit, Harwell, Didcot, Oxfordshire, OX11 0RD, United Kingdom. m.lomax@har.mrc.ac.uk

Radiat Res ; 163(1): 79-84, 2005 Jan.

Article in En | MEDLINE | ID: mdl-15606310

Subject(s)

Adenine/analogs & derivatives; Adenine/chemistry; DNA Damage/radiation effects; DNA-(Apurinic or Apyrimidinic Site) Lyase/chemistry; DNA-Formamidopyrimidine Glycosylase/chemistry; DNA/chemistry; DNA/radiation effects; Deoxyribonuclease (Pyrimidine Dimer)/chemistry; Escherichia coli Proteins/chemistry; Adenine/radiation effects; Base Sequence; DNA-(Apurinic or Apyrimidinic Site) Lyase/radiation effects; DNA-Formamidopyrimidine Glycosylase/radiation effects; Deoxyribonuclease (Pyrimidine Dimer)/radiation effects; Escherichia coli Proteins/radiation effects; Molecular Sequence Data; Purines/chemistry; Purines/radiation effects; Pyrimidines/chemistry; Pyrimidines/radiation effects; Radiation Dosage; Structure-Activity Relationship

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / DNA / Adenine / Escherichia coli Proteins / DNA-Formamidopyrimidine Glycosylase / DNA-(Apurinic or Apyrimidinic Site) Lyase / Deoxyribonuclease (Pyrimidine Dimer) Language: En Journal: Radiat Res Year: 2005 Document type: Article Affiliation country: United kingdom Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links