TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.

Ahn, Dae-ho; Crawley, Suzanne C; Hokari, Ryota; Kato, Shingo; Yang, Stacey C; Li, Jian-Dong; Kim, Young S

Ahn, Dae-ho; Crawley, Suzanne C; Hokari, Ryota; Kato, Shingo; Yang, Stacey C; Li, Jian-Dong; Kim, Young S.

Affiliation

Ahn DH; Gastrointestinal Research Laboratory, Veterans' Affairs Medical Center, San Francisco, California 94121, USA.

Cell Physiol Biochem ; 15(1-4): 29-40, 2005.

Article in En | MEDLINE | ID: mdl-15665513

Subject(s)

JNK Mitogen-Activated Protein Kinases/metabolism; Mucins/genetics; NF-kappa B/metabolism; Transcription, Genetic/drug effects; Tumor Necrosis Factor-alpha/pharmacology; Cell Line; Enzyme Activation/drug effects; Humans; Luciferases/metabolism; Mucin-2; Mucins/biosynthesis; Protein Serine-Threonine Kinases/metabolism; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-akt; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction/drug effects; Up-Regulation/drug effects; NF-kappaB-Inducing Kinase

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / NF-kappa B / Tumor Necrosis Factor-alpha / JNK Mitogen-Activated Protein Kinases / Mucins Limits: Humans Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2005 Document type: Article Affiliation country: United States Country of publication: Germany

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