Functionalized dendrimers as endotoxin sponges.

Cromer, Jens R; Wood, Stewart J; Miller, Kelly A; Nguyen, Thuan; David, Sunil A

Cromer, Jens R; Wood, Stewart J; Miller, Kelly A; Nguyen, Thuan; David, Sunil A.

Affiliation

Cromer JR; Department of Medicinal Chemistry, University of Kansas, Life Sciences Research Laboratories, 1501 Wakarusa Drive, Lawrence, KS 66049, USA.

Bioorg Med Chem Lett ; 15(5): 1295-8, 2005 Mar 01.

Article in En | MEDLINE | ID: mdl-15713373

Subject(s)

Endotoxins/antagonists & inhibitors; Lipopolysaccharides/antagonists & inhibitors; Polyamines/pharmacology; Sepsis/drug therapy; Animals; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins/chemistry; Endotoxins/pharmacology; Lipopolysaccharides/chemistry; Lipopolysaccharides/pharmacology; Macrophages/drug effects; Macrophages/metabolism; Mice; Molecular Structure; Nitric Oxide/biosynthesis; Polyamines/chemical synthesis; Polyamines/chemistry; Sepsis/chemically induced; Sepsis/prevention & control; Structure-Activity Relationship; Surface Properties

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Polyamines / Lipopolysaccharides / Sepsis / Endotoxins Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2005 Document type: Article Affiliation country: United States Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links