The COX-2 inhibitor, rofecoxib, ameliorates dextran sulphate sodium induced colitis in mice.

Martín, A R; Villegas, I; Alarcón de la Lastra, C

Martín, A R; Villegas, I; Alarcón de la Lastra, C.

Affiliation

Martín AR; Department of Pharmacology, Faculty of Pharmacy, University of Seville, Profesor García González Street, 2, 41012, Seville, Spain.

Inflamm Res ; 54(4): 145-51, 2005 Apr.

Article in En | MEDLINE | ID: mdl-15883736

Subject(s)

Colitis/chemically induced; Colitis/drug therapy; Cyclooxygenase Inhibitors/pharmacology; Dextran Sulfate/pharmacology; Lactones/pharmacology; Sulfones/pharmacology; Animals; Colitis/enzymology; Colitis/pathology; Cyclooxygenase 1/metabolism; Dinoprostone/metabolism; Immunohistochemistry; Male; Membrane Proteins/metabolism; Mice; Mice, Inbred BALB C; Prostaglandin D2/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Dextran Sulfate / Cyclooxygenase Inhibitors / Colitis / Lactones Limits: Animals Language: En Journal: Inflamm Res Journal subject: ALERGIA E IMUNOLOGIA / PATOLOGIA Year: 2005 Document type: Article Affiliation country: Spain Country of publication: Switzerland

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