The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.

Pullikuth, Ashok; McKinnon, Evangeline; Schaeffer, Hans-Joerg; Catling, Andrew D

Pullikuth, Ashok; McKinnon, Evangeline; Schaeffer, Hans-Joerg; Catling, Andrew D.

Affiliation

Pullikuth A; Department of Pharmacology, Louisiana State University Health Sciences Center, 1901 Perdido Street, New Orleans, LA 70112, USA.

Mol Cell Biol ; 25(12): 5119-33, 2005 Jun.

Article in En | MEDLINE | ID: mdl-15923628

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; MAP Kinase Kinase 1/metabolism; Protein Serine-Threonine Kinases/metabolism; rho GTP-Binding Proteins/metabolism; Actin Depolymerizing Factors; Adaptor Proteins, Signal Transducing/genetics; Amino Acid Sequence; Animals; Cell Adhesion/physiology; Cell Line; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases/metabolism; Focal Adhesions/metabolism; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 1/genetics; Microfilament Proteins/metabolism; Molecular Sequence Data; Protein Binding; Protein Serine-Threonine Kinases/genetics; Proteins/genetics; Proteins/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Rats; Sequence Alignment; Signal Transduction/physiology; Two-Hybrid System Techniques; p21-Activated Kinases; rho GTP-Binding Proteins/genetics; rho-Associated Kinases

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Serine-Threonine Kinases / Rho GTP-Binding Proteins / MAP Kinase Kinase 1 / Adaptor Proteins, Signal Transducing Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 2005 Document type: Article Affiliation country: United States Country of publication: United States

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