MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo.

Kupfer, Tinalyn M; Crawford, Megan L; Pham, Kim; Gill, Ronald G

Kupfer, Tinalyn M; Crawford, Megan L; Pham, Kim; Gill, Ronald G.

Affiliation

Kupfer TM; Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, CO 80262, USA.

J Immunol ; 175(4): 2309-16, 2005 Aug 15.

Article in En | MEDLINE | ID: mdl-16081800

Subject(s)

Autoantigens/immunology; Autoantigens/metabolism; Diabetes Mellitus, Type 1/immunology; Histocompatibility Testing; Islets of Langerhans Transplantation/immunology; Islets of Langerhans Transplantation/pathology; Animals; Antigen Presentation; CD4-Positive T-Lymphocytes/immunology; Diabetes Mellitus, Type 1/genetics; Diabetes Mellitus, Type 1/pathology; Disease Models, Animal; Female; Histocompatibility Antigens Class II/biosynthesis; Histocompatibility Antigens Class II/immunology; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Mice, Transgenic; Receptors, Antigen, T-Cell/genetics; Recurrence; Spleen/cytology; Spleen/immunology; Spleen/transplantation; Transplantation, Isogeneic

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Collection: 01-internacional Database: MEDLINE Main subject: Autoantigens / Histocompatibility Testing / Islets of Langerhans Transplantation / Diabetes Mellitus, Type 1 Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2005 Document type: Article Affiliation country: United States Country of publication: United States

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