Anxiolytic-like actions of the hexane extract from leaves of Annona cherimolia in two anxiety paradigms: possible involvement of the GABA/benzodiazepine receptor complex.

López-Rubalcava, C; Piña-Medina, B; Estrada-Reyes, R; Heinze, G; Martínez-Vázquez, M

López-Rubalcava, C; Piña-Medina, B; Estrada-Reyes, R; Heinze, G; Martínez-Vázquez, M.

Affiliation

López-Rubalcava C; Departamento de Farmacobiología, Centro de Investigación y Estudios Avanzados (CINVESTAV), Calzada. De los Tenorios 235, Col. Granjas Coapa, C.P. 14330 México D.F., Mexico. clopezr@cinvestav.mx

Life Sci ; 78(7): 730-7, 2006 Jan 11.

Article in En | MEDLINE | ID: mdl-16122763

Subject(s)

Annona/chemistry; Anti-Anxiety Agents/pharmacology; Anxiety/physiopathology; Behavior, Animal/drug effects; Receptors, GABA-A/physiology; Animals; Anxiety Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior/drug effects; GABA Agonists/pharmacology; GABA Antagonists/pharmacology; Hexanes/chemistry; Male; Mice; Muscimol/pharmacology; Picrotoxin/pharmacology; Plant Extracts/pharmacology; Plant Leaves/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Anti-Anxiety Agents / Behavior, Animal / Receptors, GABA-A / Annona Limits: Animals Language: En Journal: Life Sci Year: 2006 Document type: Article Affiliation country: Mexico Country of publication: Netherlands

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