Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice induced by camptothecins.

Pantazis, P; Hinz, H R; Mendoza, J T; Kozielski, A J; Williams, L J; Stehlin, J S; Giovanella, B C

Pantazis, P; Hinz, H R; Mendoza, J T; Kozielski, A J; Williams, L J; Stehlin, J S; Giovanella, B C.

Affiliation

Pantazis P; Stehlin Foundation for Cancer Research, St. Joseph Hospital Cancer Research Laboratory, Houston, Texas 77003.

Cancer Res ; 52(14): 3980-7, 1992 Jul 15.

Article in En | MEDLINE | ID: mdl-1617674

Subject(s)

Camptothecin/pharmacology; Melanoma/drug therapy; Animals; Body Weight/drug effects; Camptothecin/analogs & derivatives; Cell Death; Cell Division/drug effects; Drug Screening Assays, Antitumor; Graft Survival/drug effects; Male; Melanoma/pathology; Mice; Mice, Nude; Neoplasm Transplantation; Remission Induction; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Camptothecin / Melanoma Limits: Animals Language: En Journal: Cancer Res Year: 1992 Document type: Article Country of publication: United States

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