Protective effects of Polygala paniculata extract against methylmercury-induced neurotoxicity in mice.

Farina, Marcelo; Franco, Jeferson Luis; Ribas, Camila Mafalda; Meotti, Flávia Carla; Missau, Fabiana Cristina; Pizzolatti, Moacir G; Dafre, Alcir Luiz; Santos, Adair R S

Farina, Marcelo; Franco, Jeferson Luis; Ribas, Camila Mafalda; Meotti, Flávia Carla; Missau, Fabiana Cristina; Pizzolatti, Moacir G; Dafre, Alcir Luiz; Santos, Adair R S.

Affiliation

Farina M; Departamento de Bioquímica, Centro de Cieências Biológicas, Universidade Federal de Santa Catarina, 88040-900, Florianópolis, SC, Brazil. marcelofarina@zipmail.com.br

J Pharm Pharmacol ; 57(11): 1503-8, 2005 Nov.

Article in En | MEDLINE | ID: mdl-16259784

Subject(s)

Antioxidants/pharmacology; Cerebral Cortex/drug effects; Mercury Poisoning, Nervous System/prevention & control; Plant Extracts/pharmacology; Polygala; Animals; Behavior, Animal/drug effects; Cerebral Cortex/enzymology; Glutathione Peroxidase/metabolism; Glutathione Reductase/metabolism; Male; Mercury Poisoning, Nervous System/etiology; Methylmercury Compounds; Mice; Motor Activity/drug effects; Neuroprotective Agents/pharmacology; Polygala/chemistry; Thiobarbituric Acid Reactive Substances

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Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Cerebral Cortex / Mercury Poisoning, Nervous System / Polygala / Antioxidants Type of study: Etiology_studies Limits: Animals Language: En Journal: J Pharm Pharmacol Year: 2005 Document type: Article Affiliation country: Brazil Country of publication: United kingdom

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