Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin.

Kirk, Allan D; Mannon, Roslyn B; Kleiner, David E; Swanson, John S; Kampen, Robert L; Cendales, Linda K; Elster, Eric A; Wakefield, Terri; Chamberlain, Christine; Hoffmann, Steven C; Hale, Douglas A

Kirk, Allan D; Mannon, Roslyn B; Kleiner, David E; Swanson, John S; Kampen, Robert L; Cendales, Linda K; Elster, Eric A; Wakefield, Terri; Chamberlain, Christine; Hoffmann, Steven C; Hale, Douglas A.

Affiliation

Kirk AD; Transplantation Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Transplantation ; 80(8): 1051-9, 2005 Oct 27.

Article in En | MEDLINE | ID: mdl-16278585

Subject(s)

Antibodies, Monoclonal/pharmacology; Antibodies, Neoplasm/pharmacology; Guanidines/pharmacology; Immunosuppressive Agents/pharmacology; Kidney Transplantation/immunology; Lymphocyte Depletion; Transplantation Tolerance/drug effects; Adult; Alemtuzumab; Antibodies, Monoclonal, Humanized; Chemokines/genetics; Chemokines/metabolism; Creatine/blood; Female; Graft Rejection/metabolism; Humans; Kidney/cytology; Kidney/immunology; Kidney/physiology; Lymph Nodes/cytology; Lymphocyte Count; Male; Middle Aged; T-Lymphocytes/drug effects; Transcription, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Depletion / Kidney Transplantation / Transplantation Tolerance / Guanidines / Immunosuppressive Agents / Antibodies, Monoclonal / Antibodies, Neoplasm Type of study: Guideline Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Transplantation Year: 2005 Document type: Article Affiliation country: United States Country of publication: United States

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