Synthesis and reactivity with beta-lactamases of a monobactam bearing a retro-amide side chain. | Bioorg Med Chem Lett;16(4): 869-71, 2006 Feb 15. | MEDLINE

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Synthesis and reactivity with beta-lactamases of a monobactam bearing a retro-amide side chain.

Adediran, S A; Lohier, J-F; Cabaret, D; Wakselman, M; Pratt, R F.

Affiliation

Adediran SA; Department of Chemistry, Wesleyan University, Middletown, CT 06459, USA.

Bioorg Med Chem Lett ; 16(4): 869-71, 2006 Feb 15.

Article in En | MEDLINE | ID: mdl-16300942

Subject(s)

Amides/chemistry; Monobactams/chemistry; Monobactams/chemical synthesis; beta-Lactamases/chemistry; Catalysis; Enterobacter cloacae/enzymology; Hydrolysis; Kinetics; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Beta-Lactamases / Monobactams / Amides Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2006 Document type: Article Affiliation country: United States

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Collection: 01-internacional Database: MEDLINE Main subject: Beta-Lactamases / Monobactams / Amides Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2006 Document type: Article Affiliation country: United States