Sporadic inclusion-body myositis: a proposed key pathogenetic role of the abnormalities of the ubiquitin-proteasome system, and protein misfolding and aggregation.

Askanas, V; Engel, W King

Askanas, V; Engel, W King.

Affiliation

Askanas V; USC Neuromuscular Center, Department of Neurology, University of Southern California Keck School of Medicine, Good Samaritan Hospital, Los Angeles, California 90017-1912, USA. askanas@hsc.usc.edu

Acta Myol ; 24(1): 17-24, 2005 Jul.

Article in En | MEDLINE | ID: mdl-16315367

Subject(s)

Myositis, Inclusion Body/etiology; Proteasome Endopeptidase Complex/physiology; Protein Folding; Ubiquitin/physiology; Adenosine Triphosphatases; Cell Cycle Proteins/physiology; Endoplasmic Reticulum/metabolism; Heat-Shock Proteins/physiology; Humans; Muscle Fibers, Skeletal/metabolism; Mutation/physiology; Valosin Containing Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Folding / Myositis, Inclusion Body / Ubiquitin / Proteasome Endopeptidase Complex Limits: Humans Language: En Journal: Acta Myol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2005 Document type: Article Affiliation country: United States Country of publication: Italy

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