Prophylactic effects of an N- and L-type Ca2+ antagonist, cilnidipine, against cardiac hypertrophy and dysfunction in stroke-prone, spontaneously hypertensive rats.

Takemori, Kumiko; Ishida, Hiroyuki; Dote, Kensaku; Yamamoto, Kazuo; Ito, Hiroyuki

Takemori, Kumiko; Ishida, Hiroyuki; Dote, Kensaku; Yamamoto, Kazuo; Ito, Hiroyuki.

Affiliation

Takemori K; Department of Pathology, Kinki University School of Medicine, Osaka, Japan.

Can J Physiol Pharmacol ; 83(8-9): 785-90, 2005.

Article in En | MEDLINE | ID: mdl-16333380

Subject(s)

Calcium Channel Blockers/therapeutic use; Dihydropyridines/therapeutic use; Angiotensin-Converting Enzyme Inhibitors/therapeutic use; Animals; Captopril/therapeutic use; Cardiomegaly/metabolism; Cardiomegaly/prevention & control; Collagen Type III/genetics; Collagen Type III/metabolism; Fibroblast Growth Factor 2/genetics; Fibroblast Growth Factor 2/metabolism; Hypertension/complications; Hypertension/metabolism; Male; Myocardium/metabolism; Myocardium/pathology; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke/complications; Stroke/metabolism; Transforming Growth Factor beta/genetics; Transforming Growth Factor beta/metabolism; Ventricular Myosins/genetics; Ventricular Myosins/metabolism; Ventricular Remodeling/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Dihydropyridines / Calcium Channel Blockers Limits: Animals Language: En Journal: Can J Physiol Pharmacol Year: 2005 Document type: Article Affiliation country: Japan Country of publication: Canada

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