5-Fluorouracil can cross brain-blood barrier and cause encephalopathy: should we expect the same from capecitabine? A case report on capecitabine-induced central neurotoxicity progressing to coma.

Formica, V; Leary, A; Cunningham, D; Chua, Y J

Formica, V; Leary, A; Cunningham, D; Chua, Y J.

Affiliation

Formica V; Department of Medicine, Royal Marsden Hospital, Sutton, Surrey SM2 5PT, UK.

Cancer Chemother Pharmacol ; 58(2): 276-8, 2006 Aug.

Article in En | MEDLINE | ID: mdl-16333678

Subject(s)

Antineoplastic Agents/pharmacokinetics; Blood-Brain Barrier; Central Nervous System Diseases/chemically induced; Coma/chemically induced; Deoxycytidine/analogs & derivatives; Fluorouracil/pharmacokinetics; Antineoplastic Agents/adverse effects; Capecitabine; Deoxycytidine/adverse effects; Deoxycytidine/pharmacokinetics; Fluorouracil/adverse effects; Humans

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Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / Central Nervous System Diseases / Coma / Deoxycytidine / Fluorouracil / Antineoplastic Agents Limits: Humans Language: En Journal: Cancer Chemother Pharmacol Year: 2006 Document type: Article Affiliation country: United kingdom Country of publication: Germany

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