Increased expression of cyclooxygenase-2 in human pancreatic islets treated with high glucose or ligands of the advanced glycation endproduct-specific receptor (AGER), and in islets from diabetic mice.

Shanmugam, N; Todorov, I T; Nair, I; Omori, K; Reddy, M A; Natarajan, R

Shanmugam, N; Todorov, I T; Nair, I; Omori, K; Reddy, M A; Natarajan, R.

Affiliation

Shanmugam N; Gonda Diabetes Centre, Beckman Research Institute of City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA.

Diabetologia ; 49(1): 100-7, 2006 Jan.

Article in En | MEDLINE | ID: mdl-16341840

Subject(s)

Cyclooxygenase 2/genetics; Diabetes Mellitus, Experimental/physiopathology; Glucose/pharmacology; Glycation End Products, Advanced/metabolism; Islets of Langerhans/enzymology; Membrane Proteins/genetics; Receptors, Immunologic/physiology; Animals; Cyclooxygenase 1/genetics; Diabetes Mellitus, Experimental/genetics; Humans; Insulin/metabolism; Insulin Secretion; Mice; RNA, Messenger/genetics; Receptor for Advanced Glycation End Products; Reverse Transcriptase Polymerase Chain Reaction

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Immunologic / Islets of Langerhans / Glycation End Products, Advanced / Diabetes Mellitus, Experimental / Cyclooxygenase 2 / Glucose / Membrane Proteins Limits: Animals / Humans Language: En Journal: Diabetologia Year: 2006 Document type: Article Affiliation country: United States Country of publication: Germany

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