Strong HLA-DR antigen expression on cancer cells relates to better prognosis of colorectal cancer patients: Possible involvement of c-myc suppression by interferon-gamma in situ.

Matsushita, Kazuyuki; Takenouchi, Toshinao; Shimada, Hideaki; Tomonaga, Takeshi; Hayashi, Hideki; Shioya, Ayumi; Komatsu, Aki; Matsubara, Hisahiro; Ochiai, Takenori

Matsushita, Kazuyuki; Takenouchi, Toshinao; Shimada, Hideaki; Tomonaga, Takeshi; Hayashi, Hideki; Shioya, Ayumi; Komatsu, Aki; Matsubara, Hisahiro; Ochiai, Takenori.

Affiliation

Matsushita K; Department of Frontier Surgery (M9), Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuoh-ku, Chiba 260-8677, Japan. kmatsu@faculty.chiba-u.jp

Cancer Sci ; 97(1): 57-63, 2006 Jan.

Article in En | MEDLINE | ID: mdl-16367922

Subject(s)

Colorectal Neoplasms/diagnosis; Colorectal Neoplasms/metabolism; HLA-DR Antigens/metabolism; Interferon-gamma/metabolism; Proto-Oncogene Proteins c-myc/metabolism; Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Colorectal Neoplasms/genetics; Colorectal Neoplasms/pathology; Epithelium/metabolism; Epithelium/pathology; Female; Gene Expression Regulation, Neoplastic; HLA-DR Antigens/genetics; Humans; Interferon-gamma/genetics; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Proto-Oncogene Proteins c-myc/genetics; RNA, Messenger/genetics; Survival Rate; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / HLA-DR Antigens / Proto-Oncogene Proteins c-myc / Interferon-gamma Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Cancer Sci Year: 2006 Document type: Article Affiliation country: Japan

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