Inhibition of cardiac HERG potassium channels by antidepressant maprotiline.

Ferrer-Villada, Tania; Navarro-Polanco, Ricardo A; Rodríguez-Menchaca, Aldo A; Benavides-Haro, Dora E; Sánchez-Chapula, José A

Ferrer-Villada, Tania; Navarro-Polanco, Ricardo A; Rodríguez-Menchaca, Aldo A; Benavides-Haro, Dora E; Sánchez-Chapula, José A.

Affiliation

Ferrer-Villada T; Unidad de Investigación Carlos Méndez del Centro Universitario de Investigaciones Biomédicas de la Universidad de Colima, Apdo. Postal 199, C.P. 28000, Colima, Mexico.

Eur J Pharmacol ; 531(1-3): 1-8, 2006 Feb 15.

Article in En | MEDLINE | ID: mdl-16423345

Subject(s)

Antidepressive Agents, Second-Generation/pharmacology; Ether-A-Go-Go Potassium Channels/antagonists & inhibitors; Maprotiline/pharmacology; Animals; Binding Sites; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Electric Stimulation; Ether-A-Go-Go Potassium Channels/genetics; Ether-A-Go-Go Potassium Channels/physiology; Female; Gene Expression; Humans; Membrane Potentials/drug effects; Oocytes/drug effects; Oocytes/metabolism; Oocytes/physiology; Point Mutation; Xenopus

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Collection: 01-internacional Database: MEDLINE Main subject: Antidepressive Agents, Second-Generation / Ether-A-Go-Go Potassium Channels / Maprotiline Limits: Animals / Female / Humans Language: En Journal: Eur J Pharmacol Year: 2006 Document type: Article Affiliation country: Mexico Country of publication: Netherlands

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