The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.

Offe, Katrin; Dodson, Sara E; Shoemaker, James T; Fritz, Jason J; Gearing, Marla; Levey, Allan I; Lah, James J

Offe, Katrin; Dodson, Sara E; Shoemaker, James T; Fritz, Jason J; Gearing, Marla; Levey, Allan I; Lah, James J.

Affiliation

Offe K; Center for Neurodegenerative Disease, Emory University, Atlanta, Georgia 30322, USA.

J Neurosci ; 26(5): 1596-603, 2006 Feb 01.

Article in En | MEDLINE | ID: mdl-16452683

Subject(s)

Alzheimer Disease/metabolism; Amyloid beta-Peptides/biosynthesis; Amyloid beta-Protein Precursor/metabolism; Endosomes/metabolism; Membrane Transport Proteins/physiology; Receptors, LDL/physiology; Alzheimer Disease/pathology; Amyloid beta-Protein Precursor/analysis; Animals; Brain/cytology; Cell Line; Endosomes/chemistry; Humans; LDL-Receptor Related Proteins; Membrane Transport Proteins/analysis; Neurons/chemistry; Protein Transport; Rats; Receptors, LDL/analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Endosomes / Receptors, LDL / Amyloid beta-Peptides / Amyloid beta-Protein Precursor / Alzheimer Disease Limits: Animals / Humans Language: En Journal: J Neurosci Year: 2006 Document type: Article Affiliation country: United States Country of publication: United States

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