Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures.
Mini Rev Med Chem
; 6(1): 71-89, 2006 Jan.
Article
in En
| MEDLINE
| ID: mdl-16457633
Quinoxaline, quinazoline and benzimidazole based templates have been synthesized on solid-support employing different methodologies. This review enlightens academic and industrial examples of combinatorial synthesis for this type of heterocycles that appeared in the literature in the last decade. Hence, some of the important synthetic strategies for the generation of quinoxaline, quinazoline and benzimidazole based privileged structures, and the important biological activities for these heterocycles have been highlighted. Further, benzothiadiazinone, thioxoquinazolinone, cinnoline and indazole are also examined in this review.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Quinazolines
/
Quinoxalines
/
Benzimidazoles
/
Combinatorial Chemistry Techniques
Language:
En
Journal:
Mini Rev Med Chem
Journal subject:
QUIMICA
Year:
2006
Document type:
Article
Affiliation country:
India
Country of publication:
Netherlands