N omega-nitro-L-arginine attenuates the accumulation of aortic cyclic GMP and the hypotension produced by zaprinast.

Dundore, R L; Pratt, P F; O'Connor, B; Buchholz, R A; Pagani, E D

Dundore, R L; Pratt, P F; O'Connor, B; Buchholz, R A; Pagani, E D.

Affiliation

Dundore RL; Department of Cardiovascular Pharmacology, Sterling Research Group, Rensselaer, NY 12144.

Eur J Pharmacol ; 200(1): 83-7, 1991 Jul 23.

Article in En | MEDLINE | ID: mdl-1663042

Subject(s)

3',5'-Cyclic-GMP Phosphodiesterases/antagonists & inhibitors; Arginine/analogs & derivatives; Blood Pressure/drug effects; Cyclic GMP/metabolism; Hypotension/physiopathology; Muscle, Smooth, Vascular/metabolism; Purinones/pharmacology; Analysis of Variance; Animals; Aorta, Abdominal; Arginine/pharmacology; Hypotension/metabolism; Male; Muscle, Smooth, Vascular/drug effects; Nitroarginine; Radioimmunoassay; Rats; Rats, Inbred SHR

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Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Purinones / Blood Pressure / 3',5'-Cyclic-GMP Phosphodiesterases / Cyclic GMP / Hypotension / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: Eur J Pharmacol Year: 1991 Document type: Article Country of publication: Netherlands

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