Molecular alterations in the pathogenesis of endometrial adenocarcinoma. Therapeutic implications.

Cerezo, Laura; Cárdenes, Higinia; Michael, Helen

Cerezo, Laura; Cárdenes, Higinia; Michael, Helen.

Affiliation

Cerezo L; Radiation Oncology Service, La Princesa University Hospital, Autonoma University, Madrid, Spain. lcerezo.hlpr@salud.madrid.org

Clin Transl Oncol ; 8(4): 231-41, 2006 Apr.

Article in En | MEDLINE | ID: mdl-16648098

Subject(s)

Adenocarcinoma/etiology; Cell Transformation, Neoplastic/genetics; Endometrial Neoplasms/etiology; Neoplasms, Hormone-Dependent/etiology; Adenocarcinoma/blood supply; Adenocarcinoma/genetics; Adenocarcinoma/therapy; Antineoplastic Agents/therapeutic use; Combined Modality Therapy; DNA Repair/genetics; Endometrial Neoplasms/blood supply; Endometrial Neoplasms/genetics; Endometrial Neoplasms/therapy; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Genes, p53; Genomic Instability; Humans; Hysterectomy; Microsatellite Repeats; Mutagenesis; Neoplasm Proteins/genetics; Neoplasm Proteins/physiology; Neoplasms, Hormone-Dependent/blood supply; Neoplasms, Hormone-Dependent/genetics; Neoplasms, Hormone-Dependent/therapy; Neovascularization, Pathologic/genetics; Neovascularization, Pathologic/physiopathology; Oncogenes; PTEN Phosphohydrolase/genetics; PTEN Phosphohydrolase/physiology; Ploidies; Progesterone; Receptors, Estrogen/genetics; Receptors, Estrogen/physiology; Receptors, Progesterone/genetics; Receptors, Progesterone/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Cell Transformation, Neoplastic / Endometrial Neoplasms / Neoplasms, Hormone-Dependent Type of study: Etiology_studies Language: En Journal: Clin Transl Oncol Year: 2006 Document type: Article Affiliation country: Spain Country of publication: Italy

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