Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages.

Franchi, Luigi; Amer, Amal; Body-Malapel, Mathilde; Kanneganti, Thirumala-Devi; Ozören, Nesrin; Jagirdar, Rajesh; Inohara, Naohiro; Vandenabeele, Peter; Bertin, John; Coyle, Anthony; Grant, Ethan P; Núñez, Gabriel

Franchi, Luigi; Amer, Amal; Body-Malapel, Mathilde; Kanneganti, Thirumala-Devi; Ozören, Nesrin; Jagirdar, Rajesh; Inohara, Naohiro; Vandenabeele, Peter; Bertin, John; Coyle, Anthony; Grant, Ethan P; Núñez, Gabriel.

Affiliation

Franchi L; Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

Nat Immunol ; 7(6): 576-82, 2006 Jun.

Article in En | MEDLINE | ID: mdl-16648852

Subject(s)

Apoptosis Regulatory Proteins/physiology; Calcium-Binding Proteins/physiology; Caspase 1/metabolism; Flagellin/immunology; Interleukin-1/metabolism; Macrophages/immunology; Salmonella Infections/immunology; Animals; Apoptosis Regulatory Proteins/genetics; Calcium-Binding Proteins/genetics; Cytosol/metabolism; Cytosol/microbiology; Enzyme Activation; Flagellin/genetics; Macrophages/enzymology; Macrophages/microbiology; Mice; Mice, Mutant Strains; NF-kappa B/metabolism; Protein Transport; Salmonella Infections/genetics; Salmonella typhimurium/genetics; Salmonella typhimurium/immunology; Salmonella typhimurium/metabolism; Toll-Like Receptor 5/genetics; Toll-Like Receptor 5/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Salmonella Infections / Calcium-Binding Proteins / Interleukin-1 / Caspase 1 / Apoptosis Regulatory Proteins / Flagellin / Macrophages Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2006 Document type: Article Affiliation country: United States Country of publication: United States

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