Concentration-dependent effects of anticonvulsant enaminone methyl 4-(4'-bromophenyl)aminocyclohex-3-en-6-methyl-2-oxo-1-oate on neuronal excitability in vitro.

Ananthalakshmi, K V V; Edafiogho, I O; Kombian, S B

Ananthalakshmi, K V V; Edafiogho, I O; Kombian, S B.

Affiliation

Ananthalakshmi KV; Department of Applied Therapeutics, Faculty of Pharmacy, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.

Neuroscience ; 141(1): 345-56, 2006 Aug 11.

Article in En | MEDLINE | ID: mdl-16650601

Subject(s)

Action Potentials/drug effects; Anticonvulsants/pharmacology; Cyclohexanes/pharmacology; Hippocampus/cytology; Neurons/drug effects; Nucleus Accumbens/cytology; Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation/methods; Enzyme Inhibitors/pharmacology; Excitatory Postsynaptic Potentials/drug effects; Excitatory Postsynaptic Potentials/physiology; GABA Antagonists/pharmacology; In Vitro Techniques; Male; Neurons/physiology; Neurons/radiation effects; Ouabain/pharmacology; Patch-Clamp Techniques/methods; Phosphinic Acids/pharmacology; Picrotoxin/pharmacology; Propanolamines/pharmacology; Rats; Sodium Channel Blockers/pharmacology; Tetrodotoxin/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Action Potentials / Cyclohexanes / Hippocampus / Anticonvulsants / Neurons / Nucleus Accumbens Limits: Animals Language: En Journal: Neuroscience Year: 2006 Document type: Article Affiliation country: Kuwait Country of publication: United States

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