Isoliquiritigenin selectively inhibits H(2) histamine receptor signaling.

Kim, Dong-Chan; Choi, Se-Young; Kim, Sun-Hee; Yun, Bong-Sik; Yoo, Ick-Dong; Reddy, Nanga Ravi Prakash; Yoon, Ho Sup; Kim, Kyong-Tai

Kim, Dong-Chan; Choi, Se-Young; Kim, Sun-Hee; Yun, Bong-Sik; Yoo, Ick-Dong; Reddy, Nanga Ravi Prakash; Yoon, Ho Sup; Kim, Kyong-Tai.

Affiliation

Kim DC; Department of Life Science, POSTECH, San 31, Hyoja Dong, Pohang 790-784, Republic of Korea.

Mol Pharmacol ; 70(2): 493-500, 2006 Aug.

Article in En | MEDLINE | ID: mdl-16675659

Subject(s)

Chalcone/analogs & derivatives; Histamine H2 Antagonists/pharmacology; Signal Transduction/drug effects; Adenylyl Cyclases/physiology; Binding Sites; Cell Line, Tumor; Chalcone/pharmacology; Chalcones; Cyclic AMP/biosynthesis; GTP-Binding Protein alpha Subunits, Gs/physiology; Gastric Acid/metabolism; HL-60 Cells; Humans; Receptors, Adrenergic, beta-2/physiology; Receptors, Histamine H2/physiology; Signal Transduction/physiology; U937 Cells

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Chalcone / Histamine H2 Antagonists Limits: Humans Language: En Journal: Mol Pharmacol Year: 2006 Document type: Article Country of publication: United States

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