Efficacy of severe acute respiratory syndrome vaccine based on a nonhuman primate adenovirus in the presence of immunity against human adenovirus.

Zhi, Yan; Figueredo, Joanita; Kobinger, Gary P; Hagan, Heather; Calcedo, Roberto; Miller, James R; Gao, Guangping; Wilson, James M

Zhi, Yan; Figueredo, Joanita; Kobinger, Gary P; Hagan, Heather; Calcedo, Roberto; Miller, James R; Gao, Guangping; Wilson, James M.

Affiliation

Zhi Y; Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.

Hum Gene Ther ; 17(5): 500-6, 2006 May.

Article in En | MEDLINE | ID: mdl-16716107

Subject(s)

Adenoviruses, Human/immunology; Adenoviruses, Simian/immunology; Antibodies, Viral/biosynthesis; Severe acute respiratory syndrome-related coronavirus/immunology; Adult; Animals; Antibodies, Heterophile/biosynthesis; Antibodies, Viral/blood; Antibody Specificity; Genetic Vectors; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Animal; Pan troglodytes/virology; Severe Acute Respiratory Syndrome/immunology; Severe Acute Respiratory Syndrome/prevention & control; T-Lymphocytes/immunology; Vaccines, Virosome/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Adenoviruses, Human / Adenoviruses, Simian / Severe acute respiratory syndrome-related coronavirus / Antibodies, Viral Type of study: Evaluation_studies Limits: Adult / Animals / Humans Language: En Journal: Hum Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2006 Document type: Article Affiliation country: United States Country of publication: United States

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