Competitive binding of the troponin T-specific pool of caldesmon antibodies and tropomyosin to skeletal troponin T and smooth muscle caldesmon.
FEBS Lett
; 262(2): 263-5, 1990 Mar 26.
Article
in En
| MEDLINE
| ID: mdl-1692290
The fraction of polyclonal caldesmon antibodies cross-reacting with rabbit skeletal troponin T are shown to compete with smooth muscle tropomyosin for caldesmon and troponin T, as revealed by ELISA method. The epitope recognized by these antibodies was also found in Mr 77 kDa non-muscle caldesmon. These results provide functional confirmation for the suggestion that the regions of amino acid sequence homology in caldesmon isoforms and troponin T belong to the tropomyosin binding sites.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tropomyosin
/
Troponin
/
Calmodulin-Binding Proteins
/
Muscle, Smooth
Limits:
Animals
Language:
En
Journal:
FEBS Lett
Year:
1990
Document type:
Article
Country of publication:
United kingdom