Effect of a nitric oxide releasing derivative of paracetamol in a rat model of endotoxaemia.

Marshall, M; Keeble, J; Moore, P K

Marshall, M; Keeble, J; Moore, P K.

Affiliation

Marshall M; King's College London, Cardiovascular Division, UK. melanie.marshall@kcl.ac.uk

Br J Pharmacol ; 149(5): 516-22, 2006 Nov.

Article in En | MEDLINE | ID: mdl-16940991

Subject(s)

Acetaminophen/analogs & derivatives; Endotoxemia/prevention & control; Nitrates/pharmacology; Nitric Oxide/metabolism; Acetaminophen/metabolism; Acetaminophen/pharmacology; Acetylcholine/pharmacology; Animals; Aspartate Aminotransferases/blood; Blood Pressure/drug effects; Creatinine/blood; Cyclooxygenase 2/biosynthesis; Disease Models, Animal; Endotoxemia/chemically induced; Endotoxemia/metabolism; Heart Rate/drug effects; Kidney/drug effects; Kidney/enzymology; Lipopolysaccharides/toxicity; Liver/drug effects; Liver/enzymology; Lung/drug effects; Lung/enzymology; Male; Nitrates/metabolism; Nitric Oxide Synthase Type II/antagonists & inhibitors; Nitric Oxide Synthase Type II/biosynthesis; Nitrites/blood; Nitroprusside/pharmacology; Rats; Rats, Wistar; Vasodilator Agents/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endotoxemia / Acetaminophen / Nitrates / Nitric Oxide Limits: Animals Language: En Journal: Br J Pharmacol Year: 2006 Document type: Article Affiliation country: United kingdom

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