Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2.

Paruchuri, Sailaja; Yang, Jeong-Hee; Aikawa, Elena; Melero-Martin, Juan M; Khan, Zia A; Loukogeorgakis, Stavros; Schoen, Frederick J; Bischoff, Joyce

Paruchuri, Sailaja; Yang, Jeong-Hee; Aikawa, Elena; Melero-Martin, Juan M; Khan, Zia A; Loukogeorgakis, Stavros; Schoen, Frederick J; Bischoff, Joyce.

Affiliation

Paruchuri S; Department of Surgery, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA.

Circ Res ; 99(8): 861-9, 2006 Oct 13.

Article in En | MEDLINE | ID: mdl-16973908

Subject(s)

Cell Differentiation/drug effects; Endothelial Cells/cytology; Heart Valves/embryology; Mesoderm/cytology; Pulmonary Valve/cytology; Stem Cells/cytology; Transforming Growth Factor beta/pharmacology; Vascular Endothelial Growth Factor A/pharmacology; Biomarkers/metabolism; Cell Separation; Clone Cells/cytology; Clone Cells/physiology; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Endothelial Cells/physiology; Female; Fetus; Humans; Mesoderm/physiology; Middle Aged; Muscle, Smooth, Vascular/metabolism; Phenotype; Transcription, Genetic/drug effects; Transforming Growth Factor beta2; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Valve / Stem Cells / Cell Differentiation / Transforming Growth Factor beta / Endothelial Cells / Vascular Endothelial Growth Factor A / Heart Valves / Mesoderm Limits: Female / Humans / Middle aged Language: En Journal: Circ Res Year: 2006 Document type: Article Affiliation country: United States Country of publication: United States

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