Down-regulation of ABCB1 transporter by atorvastatin in a human hepatoma cell line and in human peripheral blood mononuclear cells.

Rodrigues, Alice Cristina; Curi, Rui; Britto, Luiz R G; Rebbechi, Ivanise M M; Hirata, Mario H; Bertolami, Marcelo C; Bernik, Marcia M S; Dorea, Egidio L; Hirata, Rosario D C

Rodrigues, Alice Cristina; Curi, Rui; Britto, Luiz R G; Rebbechi, Ivanise M M; Hirata, Mario H; Bertolami, Marcelo C; Bernik, Marcia M S; Dorea, Egidio L; Hirata, Rosario D C.

Affiliation

Rodrigues AC; Department of Clinical and Toxicological Analysis, Faculty of Pharmaceutical Sciences, University of Sao Paulo, Av Prof Lineu Prestes, 580, Sao Paulo, SP, Brazil. alice-rodrigues@uol.com.br

Biochim Biophys Acta ; 1760(12): 1866-73, 2006 Dec.

Article in En | MEDLINE | ID: mdl-16996216

Subject(s)

Carcinoma, Hepatocellular/metabolism; Down-Regulation/drug effects; Heptanoic Acids/pharmacology; Monocytes/metabolism; Organic Anion Transporters/metabolism; Pyrroles/pharmacology; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism; Atorvastatin; Base Sequence; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; DNA Primers; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Organic Anion Transporters/blood; RNA, Messenger/genetics; Rhodamine 123/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Monocytes / Down-Regulation / Carcinoma, Hepatocellular / Organic Anion Transporters / Heptanoic Acids Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 2006 Document type: Article Affiliation country: Brazil Country of publication: Netherlands

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