Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo.

Durchdewald, Moritz; Beyer, Tobias A; Johnson, Delinda A; Johnson, Jeffrey A; Werner, Sabine; auf dem Keller, Ulrich

Durchdewald, Moritz; Beyer, Tobias A; Johnson, Delinda A; Johnson, Jeffrey A; Werner, Sabine; auf dem Keller, Ulrich.

Affiliation

Durchdewald M; Department of Biology, Institute of Cell Biology, ETH Zurich, Zurich, Switzerland.

J Invest Dermatol ; 127(3): 646-53, 2007 Mar.

Article in En | MEDLINE | ID: mdl-17008872

Subject(s)

NF-E2-Related Factor 2/genetics; NF-E2-Related Factor 2/physiology; Reactive Oxygen Species; Ultraviolet Rays; Active Transport, Cell Nucleus; Animals; Cell Survival; Gene Expression Regulation; Genes, Reporter; Glucose Oxidase/metabolism; Hydrogen Peroxide/pharmacology; Keratinocytes/metabolism; Mice; Mice, Transgenic; Skin/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Ultraviolet Rays / Reactive Oxygen Species / NF-E2-Related Factor 2 Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Invest Dermatol Year: 2007 Document type: Article Affiliation country: Switzerland Country of publication: United States

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