Pharmacokinetics, absorption and tissue distribution of tanshinone IIA solid dispersion.

Hao, Haiping; Wang, Guangji; Cui, Nan; Li, Jing; Xie, Lin; Ding, Zuoqi

Hao, Haiping; Wang, Guangji; Cui, Nan; Li, Jing; Xie, Lin; Ding, Zuoqi.

Affiliation

Hao H; Key Lab of Drug Metabolism & Pharmacokinetics, China Pharmaceutical University, Nanjing, PR China.

Planta Med ; 72(14): 1311-7, 2006 Nov.

Article in En | MEDLINE | ID: mdl-17024606

Subject(s)

Drugs, Chinese Herbal/pharmacokinetics; Phenanthrenes/pharmacokinetics; Phytotherapy; Salvia miltiorrhiza; Abietanes; Administration, Oral; Animals; Area Under Curve; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Drugs, Chinese Herbal/administration & dosage; Humans; Infusions, Intravenous; Liver/metabolism; Lung/metabolism; Phenanthrenes/administration & dosage; Phenanthrenes/blood; Rats; Rats, Sprague-Dawley; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Phenanthrenes / Drugs, Chinese Herbal / Salvia miltiorrhiza / Phytotherapy Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Planta Med Year: 2006 Document type: Article

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